Bipolarity is important during treatment with antidepressants

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Bipolarity is important during treatment with antidepressants.

Rubino et al have identified that most (if not all) of the excess risk of suicide in a group of patients treated with venlafaxine could be explained by a higher burden of risk factors for suicide. It may be true that this group of patients had more severe or " difficult to treat " unipolar depression, but it is also possible that bipolar features in this group may be responsible for the observe...

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Bipolar depression and treatment with antidepressants.

Treatment of bipolar disorder with antidepressants tested almost exclusively in unipolar cases is common but unsupported by an appropriate body of evidence. This anomaly is highlighted by a large Taiwanese study, which implies that patients with depression difficult to treat with antidepressants are quite likely to be diagnosed subsequently with bipolar disorder.

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ژورنال

عنوان ژورنال: BMJ

سال: 2007

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.39121.846667.1f